Sunday, 19 September 2021

 

 

NEWS FLASH Tourist Places of Kashmir : Betaab Valley Also known as Switzerland of India JK coming up as golfing capital of the country : Sarmad Hafeez Dr. Jitendra Singh conducts extensive tour of Khonmoh, Srinagar Good Health and Development Go Hand in Hand : Mansukh Mandaviya Lt Governor hands over Individual and Community Forest Rights certificates to members of Tribal Communities of Jammu Division Former legislators call on Lt Governor, highlight issues of public importance Lt Governor, Manoj Sinha honours Tokyo Paralympics Participants J&K JA organizes training on “Personality Development, a Pursuit of Justice, Leadership role of a Judge as captain of ship in Trial Court” Promoting Paradise : Srinagar hosts Lions Club MICE event Roll Ball Association delegation calls on Advisor Farooq Khan DDC Chairperson Udhampur gives away motorised tricycles to specially abled persons Deputy Commissioner Udhampur, Indu Kanwal Chib listens to issues of local artisans at Panchayat Sansoo J&K Bank CMD meets PHDCCI delegation First ever coordination meeting held at District Court Complex Ganderbal Fit India Movement : DC Ramban flags off Patnitop Hill Marathon DC Ganderbal inspects progress on various School Education projects DDC Anantnag , Dr. Piyush Singla inaugurates inter-zonal tournaments Divisional Commissioner Kashmir, Pandurang Kondbara Pole for 100% vaccination of staff in govt, private offices Divisional Commissioner Kashmir, Pandurang Kondbara Pole conducts site visit of Srinagar riverfront project Divisional Commissioner Kashmir, Pandurang Kondbara Pole invokes Imams, Khateebs for CAB enforcement in Srinagar DC Kupwara, Imam Din visits fire victims at Nagri Malpora

 

How diabetes, cancer & pesticide exposure raises Covid risk

 Health, Study, New York, Research, Researchers, World News, Coronavirus, COVID 19, Novel Coronavirus, Covaxin, Covishield, Covid-19 Vaccine, Covid-19 Vaccine in India, COVID-19 Vaccination, COVID Vaccination, Coronavirus Vaccine, Oxygen, #OxygenCylinders, #oxygen, Oxygen Cylinders, diabetes, cancer

Web Admin

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5 Dariya News

New York , 27 Apr 2021

People with metabolic diseases like Type-2 diabetes and cancer as well as those exposed to organophosphate pesticides can be at an increased risk of Covid-19 infection, finds a new study performed in human lung airway cells.The study, led by Saurabh Chatterjee and team from the University of South Carolina in the US, identified a basic mechanism linked with inflammation that could increase susceptibility to Covid-19 infection among people exposed to organophosphates.The findings showed that people with Type-2 diabetes and cancer may also be at increased risk to Covid because they tend to exhibit the same type of inflammation.Exposure to organophosphate pesticides causes Gulf War Illness -- a cluster of medically unexplained chronic symptoms that can include fatigue, headaches, joint pain, indigestion, insomnia, dizziness, respiratory disorders and memory problems.The team examined whether exposure to the organophosphate pesticide chlorpyriphos and increased levels of interleukin 6 (IL-6) could increase risk of SARS-CoV-2 infection.For six hours, they exposed human lung airway epithelial cells to either IL-6 or chlorpyriphos or to both in combination. 

Another group of cells received no exposure to serve as a control.The researchers then treated the cells with the spike proteins that cover the outside of SARS-CoV-2. During infection, spike proteins bind with angiotensin converting enzyme 2 (ACE2) receptors to our cells, starting a process that allows the virus to release its genetic material into the healthy cell.They found that cells exposed to IL-6 and the pesticide exhibited increased apoptosis -- or controlled cell death -- when the SARS-CoV-2 spike protein was present.The cells exposed to both the pesticide and IL-6 also had significantly more ACE2 expression on the apical cell surface compared to cells that were unexposed or exposed to the pesticide alone. The apical membrane of airway cells faces the interior of the airway while the basolateral membrane touches the surrounding tissues. Increased ACE2 receptor expression on the apical surface means more viruses will attach to the cells, the researchers explained."Since people with obesity, Type-2 diabetes or cancer also have high circulatory IL-6 levels, we think people with these conditions will also have increased susceptibility to SARS-CoV-2 infection because of increased translocation of ACE2 receptor to the apical cell surface," Chatterjee said.The findings will be presented at the virtual Experimental Biology (EB) 2021 meeting to be held April 27-30.

 

Tags: Health , Study , New York , Research , Researchers , World News , Coronavirus , COVID 19 , Novel Coronavirus , Covaxin , Covishield , Covid-19 Vaccine , Covid-19 Vaccine in India , COVID-19 Vaccination , COVID Vaccination , Coronavirus Vaccine , Oxygen , #OxygenCylinders , #oxygen , Oxygen Cylinders , diabetes , cancer

 

 

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