Thursday, 29 February 2024

 

 

LATEST NEWS Governor Banwari Lal Purohit Punjab confers Honorary doctorate on MP Vikram Sahney LPU hosted two-day Indian Entrepreneurship Conclave- IECon’24 Shark Tank India Season 3: Aastey Pitch Update And Deal Indian Actor And Comedian Sunil Grover Net Worth 2024 National Science Day Celebration at BELA College of Pharmacy Vigilance Bureau Arrests ASI For Taking Rs 6 Lakh Bribe Abu Dhabi Accountability Authority Achieves CIPS Certification in Ethical Procurement and Supply Lt Governor releases book “Empowering Women in India: Exploring Regional Genderscapes” Anu Guptar, Sanjay Gandotra calls on Lieutenant Governor Manoj Sinha Atal Dulloo takes stock of the solarisation mission Atal Dulloo reviews industrial development in the UT Advisor Rajeev Rai Bhatnagar reviews physical, financial progress of various schemes in SDD Chairperson KVIB Dr. Hina Shafi Bhat chairs awareness camp at Palli Mandeep Kaur assesses progress on Urban Development in Katra MSME, DF Office Jammu hosts awareness event on PM Vishwakarma Scheme at Kishtwar Farmers provided Agricultural Equipment, Hi-Tech Infrastructure under HADP in Udhampur District Div Com Jammu reviews status of de-silting, maintenance of Irrigation canals in Jammu, Samba and Kathua Div Com discusses measures for smooth traffic movement on Dalwas-Ramban stretch of National Highway Div Com Jammu and ADGP discuss measures for smooth traffic movement on Dalwas-Ramban stretch of National Highway Mann Government on spree to promote Punjab's cultural heritage and tourism: Chetan Singh Jouramajra State Government's Efforts To Restore Punjab's Lost Glory In Sports Begin To Bear Fruit

 

Lung, heart stem cell study can pave way for new Covid treatments

Omicron Variant, Delta Plus Covid variant, Delta Covid-19 variant, Coronavirus, Health, Research, Study, Researchers, COVID 19, Novel Coronavirus, Fight Against Corona, Covaxin, Covishield, Oxygen, SARS-CoV-2, Sputnik V, Oxygen Plants, Pfizer, Astra Zeneca, Oxygen Concentrator, Remdesivir, Liquid Medical Oxygen, Oximeter
Listen to this article

Web Admin

Web Admin

5 Dariya News

Sydney , 14 Jun 2023

Researchers have used heart and lung stem cells infected with the virus that causes Covid-19 to better understand how the disease impacts different organs, paving the way for more targeted treatments.

The research, co-led by Murdoch Children's Research Institute and the Peter Doherty Institute for Infection and Immunity (Doherty Institute) in Australia, found the responses to SARS-CoV-2 varied significantly depending on the cell type, allowing the team to identify effective antiviral drugs to treat infection in heart and lung cells.

To understand the impact of SARS-CoV-2 on different organs, the team engineered human stem cells in the lab into lung and heart cells and infected them with the virus.The findings, published in the journal Stem Cell Reports, showed that the heart and lungs exhibit distinct antiviral and toxicity profiles that could inform better Covid therapies and treat its complications.

"Our findings highlight the importance of using several cell types for the evaluation of antiviral drugs to determine the best drug combinations for effective treatment of a virus that affects multiple organ systems," said David Elliott, Associate Professor at Murdoch Institute.

While SARS-CoV-2 primarily infected the respiratory tract, lung and cardiac complications occur in severe cases of Covid-19.Cardiac complications are observed in up to 78 per cent of recovered Covid patients and ongoing myocardial inflammation in 60 per cent of patients.

"Although Covid-19 vaccines are highly effective in preventing severe illness and death, antiviral compounds are required for the treatment of Covid-19, particularly with the emergence of variant viruses that evade immunity," said Professor Kanta Subbarao, from the Doherty Institute.

"To date, only a handful of drugs have been approved for use in hospitalised Covid-19 patients and more are needed."The study also looked at approved drugs for treating Covid, including Remdesivir and Molnupiravir, with some found to be more effective than others at treating infection in lung and heart stem cells.

It identified Alectinib and SPHINX31 as promising antivirals for SARS-CoV-2 in both heart and lung cells."We have provided valuable insights into virus-host interactions in tissues that are significantly affected in Covid-19, with implications that will further therapeutic options," Professor Subbarao said.

 

Tags: Omicron Variant , Delta Plus Covid variant , Delta Covid-19 variant , Coronavirus , Health , Research , Study , Researchers , COVID 19 , Novel Coronavirus , Fight Against Corona , Covaxin , Covishield , Oxygen , SARS-CoV-2 , Sputnik V , Oxygen Plants , Pfizer , Astra Zeneca , Oxygen Concentrator , Remdesivir , Liquid Medical Oxygen , Oximeter

 

 

related news

 

 

 

Photo Gallery

 

 

Video Gallery

 

 

5 Dariya News RNI Code: PUNMUL/2011/49000
© 2011-2024 | 5 Dariya News | All Rights Reserved
Powered by: CDS PVT LTD