Monday, 28 November 2022

 

 

LATEST NEWS Does Naga Chaitanya Have An Affair with THIS South Indian Actress? Vijay Hazare Trophy : Ruturaj Gaikwad smashes seven sixes in an over, enters record books WhatsApp to launch 'Message Yourself' feature in India Rahul Dravid, Rohit Sharma have the responsibility to shield Arshdeep Singh from an overdose of advice : Brett Lee Indian handicraft exports rising steadily : Piyush Goyal 'Bigg Boss 16': Nimrit Kaur Ahluwalia becomes new captain of the house, riles Tina Datta TV star Pooja Gor talks about how to do an 'I Can't Hear You' audio show Afghanistan confirm spot in 2023 ODI World Cup after wash-out in second ODI against Sri Lanka South Indian Cinema Superstar Dhanush Soon Landing With His New Movie. Know More About The News Cameron Green confirms he is available for IPL auction, looking forward to playing in 2023 edition David Warner warns Cameron Green over hectic schedule in 2023, including IPL participation Ram 'RRR' Charan to star in Buchi Babu Sana's pan-India project 4 killed in road accident in J&K's Udhampur Arvind Kejriwal claims AAP's Isudan, Gopal and Alpesh are winning big in Gujarat 5.4 mn Twitter users' data leaked online, to grow even bigger 'Cirkus' teaser packs in signature Rohit Shetty entertainment Learned from Mahendra Singh Dhoni how to stay neutral even when you are winning : Ruturaj Gaikwad Ayushmann Khurrana poses in front of SRK's Mannat; gets mobbed by fans New Zealand Prime Minister Jacinda Ardern announces multimillion-dollar package to combat retail crime, reoffending Elon Musk fixes 'slight degradation of service' on Twitter Rishab Pant not utilising his chances, suggests giving him a break to reinvent his game : Krishnamachari Srikkanth

 

Aussie scientists unravel vital role of 'junk' DNA

Health,  Study,  Sydney,  Research,  Researchers,  World News, DNA

Web Admin

Web Admin

5 Dariya News

Sydney , 23 Mar 2022

A piece of DNA, previously considered as 'junk' material by scientists, could be the key to extinguishing fear-related memories for people with post-traumatic stress disorder (PTSD) and phobias, according to a new study led by Australian researchers.Team leader associate professor Timothy Bredy, a neuroscientist at the Queensland Brain Institute (QBI) which is affiliated with the University of Queensland, said the discovery could ultimately help in the development of a therapy to target areas in the brain that directly modify disturbing memories.Their findings, published in the journal Cell Reports on Wednesday, are based on a study into the impact of trauma on a genome, which is the complete set of genes or genetic material in a cell, Xinhua news agency reported.Bredy explained how researchers had tested mice that had been trained to respond to stimuli in a certain way, Xinhua news agency reported.

"We behaviourally train mice and then, immediately following the experience, we examine specific cell types from their prefrontal cortex to see how genes are expressed in response to experience," Bredy said, adding that the results had defied expectations."Until recently, scientists thought most of our genes were made up of 'junk' DNA, which essentially didn't do anything," he said. "But when we began to explore these regions, we realised most of the genome is active."Bredy and his team, including scientists from China and the US, were "very much surprised" by how many long non-coding RNA (lncRNAs) were actively expressed in response to the experience.He said their breakthrough had been made possible by the use of a powerful new sequencing approach which "shines a very bright light on regions of the genome that one cannot see with standard sequencing methods".

"It is a really interesting way to zero in on sites within the genome that would otherwise be masked," Bredy said. "It's like harnessing the power of the Hubble Telescope to peer into the unknown of the brain."The technology enabled them to identify 433 lncRNAs from relatively unknown regions of the human genome.Bredy said a new gene, called ADRAM (which stands for Activity Dependent lncRNA Associated with Memory) acted as a "scaffold for molecules inside the cell" and helped coordinate the formation of fear-extinction memory."Our findings suggest that lncRNAs provide a bridge, linking dynamic environmental signals with the mechanisms that control the way our brains respond to fear," he said."Our next steps are to continue exploring lncRNA activity in the brain to look at their roles in different compartments of the cell and to harness the selectivity of lncRNAs ... to treat cognitive impairment disorders."

 

Tags: Health , Study , Sydney , Research , Researchers , World News , DNA

 

 

related news

 

 

 

Photo Gallery

 

 

Video Gallery

 

 

5 Dariya News RNI Code: PUNMUL/2011/49000
© 2011-2022 | 5 Dariya News | All Rights Reserved
Powered by: CDS PVT LTD