Friday, 26 April 2024

 

 

LATEST NEWS MD Markfed Visits Mandis In Ludhiana, Moga And Ferozepur Along With Dcs To Ensure Smooth Procurement Operations ADC Viraj S Tidke Launches Voter Awareness Campaign for Banking Customers from PNB DAC Mohali Branch Haryana Chief Secretary Reviews Heatwave Preparedness and Election Arrangements HPF&AS Trainee officers call on Governor Shiv Pratap Shukla Every Citizen's Vote: A beacon of hope for a better tomorrow - Chief Electoral Officer Anurag Agarwal Through C-Vigil, citizens are keeping a vigilant eye on the elections Renowned Bollywood Writer Javed Akhtar inspires Students at LPU's Media Fest "Xpressions-2024" IPL Player Tilak Varma Net Worth [April 2024] | 5 Dariya News 6 Top Priya Mishra Web Series To Watch [April- 2024] | 5 Dariya News Nehal Wadhera Net Worth 2024 (IPL Player) When the Congress government came, 50% reservation to women and MSP to farmers : Anuma Acharya AAP’s hard hitting attack on Channi: Post 1st June you will be arrested Manish Tiwari will win by a Huge margin: Jarnail Singh Amman is back with Romantic Track 'Dil Kare' Congress is working to divide the country in the name of religion and caste: Dr. Subhash Sharma PM Modi synonymous with trust, hope, credibility: Devender Singh Rana Atal Dulloo reviews the working & Public Outreach activities of Information Department General, Police Observer interact with Zonal, Sectoral Magistrates, BLOs of district Reasi Div Com Jammu, ADGP visit Rajouri, review preparations for elections Lt Governor addresses seminar on National Education Policy 2020 at Ghazipur DC Bandipora Shakeel ul Rehman Rather reviews Floriculture, Fisheries, Sericulture Departments

 

Explained: How antibodies attack spike protein of Covid variants

Delta Plus Covid variant, Delta Covid-19 variant, Coronavirus, Health, Research, Study, Researchers, COVID 19, Novel Coronavirus, Fight Against Corona, Covaxin, Covishield, Oxygen, Oxygen Cylinders, SARS-CoV-2, Sputnik V, Oxygen Plants, Pfizer, Astra Zeneca, Oxygen Concentrator, Remdesivir, Oxygen supply, Liquid Medical Oxygen, Oximeter
Listen to this article

Web Admin

Web Admin

5 Dariya News

New York , 24 Jul 2021

A team of US researchers has created an "atlas" that charts how 152 different antibodies attack a major piece of the SARS-CoV-2 machinery, the spike protein, as it has evolved since 2020.The study, published in the journal Cell, highlights antibodies that are able to neutralise the newer strains, while identifying regions of the spike protein that have become more resistant to attack."Emerging data show that vaccines still confer some protection from new SARS-CoV-2 variants, and our study shows how that works from an antibody standpoint," said Duane Wesemann, of the Division of Allergy and Clinical Immunology and Division of Genetics at Brigham and Women's Hospital."These data can help us think about what the best kind of booster vaccine might be by studying how the repertoire of human antibodies recognises the spike protein," Wesemann added.The researchers examined the antibody-producing Memory B cells of 19 patients who were infected with SARS-CoV-2 in March of 2020, before the emergence of new variants.They studied how these antibodies, as well as other antibodies that have been characterised by researchers, bind to spike protein models of the B.1.1.7 (Alpha), B.1351 (Beta) and P.1 (Gamma) variants of SARS-CoV-2, which were first identified in the UK, South Africa, and Brazil, respectively.An analysis of the Delta variant is currently underway.Overall, the hundreds of antibodies they studied largely bind to seven major "footprints" on the spike protein.While many of these antibodies "compete" to bind to the same regions of the early version of the SARS-CoV-2 spike protein, when it comes to newer strains, some of these antibodies lose their potency while others emerge as broadly responsive neutralisers, the researchers said.In particular, antibodies binding to two of these spike protein regions, dubbed RBD-2 and NTD-1, were the most potent neutralisers of initial forms of the spike protein.The B.1.351 spike variant proved to exhibit the greatest ability to evade existing antibody arsenals, escaping many RBD-2- and NTD-1-binding antibodies. Some antibodies binding another region, called S2-1, could recognise spike proteins from more distantly related viruses such as MERS, SARS, and common cold coronaviruses, the team explained."Now that we can identify the antibodies that are more broadly reactive to all of the variants, we can think about how to elicit them more strongly in a vaccine," Wesemann said.

 

Tags: Delta Plus Covid variant , Delta Covid-19 variant , Coronavirus , Health , Research , Study , Researchers , COVID 19 , Novel Coronavirus , Fight Against Corona , Covaxin , Covishield , Oxygen , Oxygen Cylinders , SARS-CoV-2 , Sputnik V , Oxygen Plants , Pfizer , Astra Zeneca , Oxygen Concentrator , Remdesivir , Oxygen supply , Liquid Medical Oxygen , Oximeter

 

 

related news

 

 

 

Photo Gallery

 

 

Video Gallery

 

 

5 Dariya News RNI Code: PUNMUL/2011/49000
© 2011-2024 | 5 Dariya News | All Rights Reserved
Powered by: CDS PVT LTD