Thursday, 26 May 2022

 

 

LATEST NEWS Rohit Shetty & Ranveer Singh Once Again Join Hands For Upcoming Project. Details Inside The Cost Of TV In Shah Rukh Khan’s Mannat Will Surely amaze You. Tweeple Says, ‘I Feel Poor Now’ IPL 2022 : Royal Challengers Bangalore vs Rajasthan Royals will be a royal encounter as both teams want to win badly, says Ravi Shastri Governments, companies own 8% of all Bitcoin worth $46 bn in the world IPL 2022: What Rajat Patidar did was very, very special, says Virat Kohli on Royal Challengers Bangalore's unlikely hero Vinod Kambli, Mahesh Manjrekar at the grand launch of Milind Narvekar and Anil Parab’s Supremo Trophy Cricket Tourney Vijay Deverakonda only Telugu hero to make it to Karan Johar's birthday bash Arrest of 4 Khalistani terrorists: MHA hands over case to NIA NASA shares one last selfie from Insight Mars lander IPL 2022 : Harshal Patel admits to being nervous while defending 35 off 18 balls against Lucknow Super Giants Pankaj Tripathi had a tough time shooting in Ladakh for 'Gulkanda Tales' Telangana Chief Minister K. Chandrasekhar Rao flies to Bangalore before Prime Minister Narendra Modi arrival in Hyderabad Naomi Campbell supports Kate Moss for testifying in Depp's trial Rajiv Adatia on doing 'Khatron Ke Khiladi 12': I am anxious and nervous India to promote millets, millet products for global market Canada confirms 16 monkeypox cases Ewan McGregor on how he prepped for 'Obi-Wan Kenobi' Harry Styles halted sold-out London show to help fan in distress Kate Moss denies rumour Johnny Depp once pushed her down the stairs, court hears Kamal Haasan's new movie 'Vikram' gets U/A certificate Akshay Kumar says Manushi Chhillar has a sharp memory

 

Indian-origin scientist creates 1st molecular structure of Omicron protein

Omicron Variant, Delta Plus Covid variant, Delta Covid-19 variant, Coronavirus, COVID 19, Novel Coronavirus, Fight Against Corona, Covaxin, Covishield, Covid-19 Vaccine, Oxygen, Oxygen Cylinders, SARS-CoV-2, Sputnik V, Oxygen Plants, Pfizer, Astra Zeneca, Oxygen Concentrator, Remdesivir, Covifor, Oximeter

Web Admin

Web Admin

5 Dariya News

Toronto , 22 Jan 2022

An Indian-origin researcher at University of British Columbia (UBC) has created the world's first molecular-level structural analysis of the Omicron variant spike protein.

Published in the Science journal, the analysis which is done at near atomic resolution using cryo-electron microscopy, reveals how the heavily mutated Omicron variant attaches to and infects human cells."Understanding the molecular structure of the viral spike protein is important as it will allow us to develop more effective treatments against Omicron and related variants in the future," said the study's lead author Dr Sriram Subramaniam, a professor at UBC's department of biochemistry and molecular biology."By analysing the mechanisms by which the virus infects human cells, we can develop better treatments that disrupt that process and neutralise the virus," Subramaniam added.The spike protein, which is located on the outside of a coronavirus, enables SARS-CoV-2 to enter human cells.The Omicron variant has an unprecedented 36 mutations on its spike protein three to five times more than previous variants.

The structural analysis revealed that several mutations create new salt bridges and hydrogen bonds between the spike protein and the human cell receptor known as ACE2.The new bonds appear to increase binding affinity  how strongly the virus attaches to human cells."The findings show that Omicron has greater binding affinity than the original virus, with levels more comparable to what we see with the Delta variant," said Subramaniam."It is remarkable that the Omicron variant evolved to retain its ability to bind with human cells despite such extensive mutations."The Omicron spike protein exhibits increased antibody evasion.In contrast to previous variants, Omicron showed measurable evasion from all six monoclonal antibodies tested, with complete escape from five.The variant also displayed increased evasion of antibodies collected from vaccinated individuals and unvaccinated Covid-19 patients.Notably, Omicron was less evasive of the immunity created by vaccines, compared to immunity from natural infection in unvaccinated patients. This suggests that vaccination remains our best defence," Subramaniam informed.

 

Tags: Omicron Variant , Delta Plus Covid variant , Delta Covid-19 variant , Coronavirus , COVID 19 , Novel Coronavirus , Fight Against Corona , Covaxin , Covishield , Covid-19 Vaccine , Oxygen , Oxygen Cylinders , SARS-CoV-2 , Sputnik V , Oxygen Plants , Pfizer , Astra Zeneca , Oxygen Concentrator , Remdesivir , Covifor , Oximeter

 

 

related news

 

 

 

Photo Gallery

 

 

Video Gallery

 

 

5 Dariya News RNI Code: PUNMUL/2011/49000
© 2011-2022 | 5 Dariya News | All Rights Reserved
Powered by: CDS PVT LTD