Wednesday, 18 May 2022

 

 

LATEST NEWS NephroPlus calls out that Hypertension is a leading cause of kidney disease and kidney failure Decoding the link between hypertension, heart diseases and stroke DC asked the health dept to adopt result oriented approach for drug de addiction and rehabilitation World Hypertension Day : Just 36 percent women, 31 percent men have normal blood pressure in J&K, reveal official figures Governor Rajendra Vishwanath Arlekar presides over 25th senate meeting at CSK Agriculture University Every child has right to quality education : Rajendra Vishwanath Arlekar LPU Boxer confirms Medal at Women’s World Boxing Championships- 2022 in Turkey Interactive workshop on Employment Generation, Skill Development & Training organised Deputy Commissioner urges school principals, teachers & parents to encourage children above 12 years to get vaccinated Mann government in action mode….‘Janta ka CM, Janta ke beech’ Actress Sara Ali Khan gives glimpse of her trekking in Pahalgam District Environment Committee meeting chaired by Deputy Commissioner Red Cross Day observed at Indian Red Cross Society Kapurthala Umran Malik breaks Jasprit Bumrah's record, becomes youngest Indian bowler to pick 20 wickets in an IPL season Nothing more beautiful than a film that connects people: Fatima Sana Shaikh on 'Modern Love: Mumbai' New Zealand all-rounder Amelia Kerr returns to Brisbane Heat for Women's Big Bash League Minor girl allegedly kidnapped, raped in Jammu & Kashmir's Anantnag Madhya Pradesh Chief Minister Shivraj Singh Chouhan to launch 'Har Ghar Nal, Har Ghar Jal' scheme in MP's Rewa Instagram likely testing new Stories layout that hides excessive posts Arjun Kapoor & Malaika Arora To Marry Soon? Wedding Date Inside Jagjeet Sandhu Works With Diljit Dosanjh In Jaswant Singh Khalra’s Biopic. Details Inside

 

IIT Mandi team finds Himalayan plant to help fight Covid infection

Omicron Variant, Delta Plus Covid variant, Delta Covid-19 variant, Coronavirus, Health, Research, Study, Researchers, COVID 19, Novel Coronavirus, Fight Against Corona, Covaxin, Covishield, Oxygen, SARS-CoV-2, Sputnik V, Oxygen Plants, Pfizer, Astra Zeneca, Oxygen Concentrator, Remdesivir, Liquid Medical Oxygen, Oximeter

Web Admin

Web Admin

5 Dariya News

Mandi , 17 Jan 2022

Researchers from the Indian Institute of Technology (IIT) Mandi have identified phytochemicals in the petals of a Himalayan plant that could potentially be used to treat Covid-19 infections.Besides regular vaccination against Covid, there is a worldwide search for non-vaccine medicines that can prevent viral invasion of the human body.

"Among the different types of therapeutic agents being studied, phytochemicals chemicals derived from plants are considered particularly promising because of their synergistic activity and natural source with fewer toxicity issues," said Dr. Shyam Kumar Masakapalli, Associate Professor, BioX Centre, School of Basic Science, IIT Mandi, in a statement.The team found petals of the Himalayan Buransh plant, scientifically called Rhododendron arboreum, are consumed in various forms by the local population for its varied health benefits.

Thus, scientists from IIT Mandi together with those from the International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, set out to scientifically test the extracts containing various phytochemicals in it, with particular focus on antiviral activity.The researchers extracted the phytochemicals from the Buransh petals and performed biochemical assays and computational simulation studies to understand its antiviral properties."We have profiled and investigated the phytochemicals of Rhododendron arboreum petals sourced from Himalayan flora and have found it to be a promising candidate against the Covid virus," said Dr Ranjan Nanda, from Translational Health Group at ICGEB.The findings have been recently published in the journal, Biomolecular Structure and Dynamics.Hot water extracts from the Buransh petals were found to be rich in quinic acid and its derivatives. 

Molecular dynamics studies showed that these phytochemicals have two kinds of effects against the virus.They are bound to the main protease an enzyme that plays an important role in viral replication and to the Human Angiotensin-Converting Enzyme-2 (ACE2) that mediates viral entry into the host cells.The researchers also showed through experimental assays that non-toxic doses of the petal extracts can inhibit Covid infection in Vero E6 cells (cells derived from kidney of an African green monkey that are commonly used to study infectivity of virus and bacteria), without any adverse effects on the cells themselves.The findings support the urgent need for further scientific studies aimed at finding specific bioactive drug candidates from R. arboreum, in vivo and clinical trials against Covid-19.The research team also plans to carry out additional studies to understand the precise mechanism of inhibition of Covid-19 replication by specific phytochemicals from Buransh petals.

 

Tags: Omicron Variant , Delta Plus Covid variant , Delta Covid-19 variant , Coronavirus , Health , Research , Study , Researchers , COVID 19 , Novel Coronavirus , Fight Against Corona , Covaxin , Covishield , Oxygen , SARS-CoV-2 , Sputnik V , Oxygen Plants , Pfizer , Astra Zeneca , Oxygen Concentrator , Remdesivir , Liquid Medical Oxygen , Oximeter

 

 

related news

 

 

 

Photo Gallery

 

 

Video Gallery

 

 

5 Dariya News RNI Code: PUNMUL/2011/49000
© 2011-2022 | 5 Dariya News | All Rights Reserved
Powered by: CDS PVT LTD