Tuesday, 28 September 2021

 

 

LATEST NEWS Union MoRTH Nitin Gadkari, Lt Governor lay foundation for four National Highway Projects worth Rs 3612 Cr Two-day visit of Union Minister for I&B to Ganderbal concludes Rs 200 Cr. allotted for Development of sports infrastructure on modern pattern in U.T of J&K : Anurag Thakur Ramdas Athawale takes stock of implementation of social welfare schemes in Jammu Union Minister of State Tribal Affairs Renuka Singh visits District Kulgam Union MoS Road Transport and Highways, Civil Aviation Dr. V. K. Singh visits Anantnag Union MoS, Tribal Affairs Renuka Singh interacts with DDC, BDC members, other PRI representatives at Kulgam Union Minister of State for Finance inaugurates various development projects in Jammu Union MoS Jal Shakti, Tribal Affairs, Bishweswar Tudu concludes visit to Kishtwar Lt Governor visits “The Paradise Fest” organized to celebrate World Tourism Week Charanjit Singh Channi Asks Administrative Secretaries To Prepare 100 Days Roadmap To Ensure Holistic Development Of State Charanjit Singh Channi Calls Emergency Meeting On Farmers' Issues In Wake Of 'Bharat Bandh' Call Given By Samyukt Kisan Morcha Charanjit Singh Channi Curtails Security Of VVIPs SSP Pulwama Gulam Jeelani Wani, assume charge, held introductory meeting with Visits various posts of district police Pulwama Parliamentarian Delegation arriving to interact with common people in Kashmir Assam's highest civilian award for national integration to be conferred by V-P Naidu RSS statement on Amazon irrelevant : Randeep Singh Surjewala India-US enhanced ties to boost research, health management : Bharati Pravin Pawar Shafali Verma and Radha Yadav sign up for Sydney Sixers in WBBL England cricketer Moeen Ali retires from Test cricket Don't see that aggressiveness in this Mumbai Indians side : Zaheer Khan

 

Why do some people get severe Covid?

Delta Plus Covid variant, Delta Covid-19 variant, Coronavirus, Health, Research, Study, Researchers, COVID 19, Novel Coronavirus, Fight Against Corona, Covaxin, Covishield, Oxygen, Oxygen Cylinders, SARS-CoV-2, Sputnik V, Oxygen Plants, Pfizer, Astra Zeneca, Oxygen Concentrator, Remdesivir, Oxygen supply, Liquid Medical Oxygen, Oximeter

Web Admin

Web Admin

5 Dariya News

New York , 24 Jul 2021

The body's first encounter with SARS-CoV-2, the virus behind Covid-19, happens in the nose and throat, or nasopharynx, thus it may help determine who will develop severe Covid disease and who will get through with mild or no illness, according to a study.The study, led by a team of researchers at the Massachusetts Institute of Technology, Boston Children's Hospital (BCH); and the Universities of Mississippi and Harvard found that people who develop severe Covid-19 have markedly blunted antiviral responses in the nasopharynx."Why some people get more sick than others has been one of the most puzzling aspects of this virus from the beginning," said researchers, including Jose Ordovas-Montanes, of Boston Children's Hospital."Many studies looking for risk predictors have looked for signatures in the blood, but blood may not really be the right place to look," Ordovas-Montanes added.For the study, published in the journal Cell, the team comprehensively mapped SARS-CoV-2 infection in the nasopharynx. They obtained samples from the nasal swabs of 35 adults with Covid-19 from April to September 2020, ranging from mildly symptomatic to critically ill.

They also got swabs from 17 control subjects and six patients who were intubated but did not have Covid-19.When the team compared nasopharyngeal swabs from people with different severity of Covid-19 illness, they found that in people with mild or moderate Covid-19, epithelial cells showed increased activation of genes involved with antiviral responses, especially genes stimulated by type I interferon, a very early alarm that rallies the broader immune system.Further, in people who developed severe Covid-19, requiring mechanical ventilation, antiviral responses were markedly blunted.In particular, their epithelial cells had a muted response to interferon, despite harbouring high amounts of virus. At the same time, their swabs had increased numbers of macrophages and other immune cells that boost inflammatory responses."Everyone with severe Covid-19 had a blunted interferon response early on in their epithelial cells, and were never able to ramp up a defense," said Ordovas-Montanes."Having the right amount of interferon at the right time could be at the crux of dealing with SARS-CoV-2 and other viruses."

 

Tags: Delta Plus Covid variant , Delta Covid-19 variant , Coronavirus , Health , Research , Study , Researchers , COVID 19 , Novel Coronavirus , Fight Against Corona , Covaxin , Covishield , Oxygen , Oxygen Cylinders , SARS-CoV-2 , Sputnik V , Oxygen Plants , Pfizer , Astra Zeneca , Oxygen Concentrator , Remdesivir , Oxygen supply , Liquid Medical Oxygen , Oximeter

 

 

related news

 

 

Photo Gallery

 

 

Video Gallery

 

 

5 Dariya News RNI Code: PUNMUL/2011/49000
© 2011-2021 | 5 Dariya News | All Rights Reserved
Powered by: CDS PVT LTD