Tuesday, 29 November 2022



LATEST NEWS Ammy Virk Digs At Sonam Bajwa’s Cricket Knowledge. Says, ‘You’ll Be The Next President Of ICC’ District Ramban bags National e-Governance Silver award for e-Suvidha App District Admin Rajouri, DECC organise Job Fair PSPS Govt. PG Women College organises extension Lecture on “Digital Marketing: Opportunities & Threats” DC Doda Vishesh Paul Mahajan reviews progress on key indicators of Revenue department Students of Ramban shine in Divisional Level Kala Utsav competition Drug & Food Control Organization inspects medical stores in Ramban My Town My Pride -2.0 : DC Kathua reviews preparations for "Jan Abhiyaan Shehri" Agriculture Directorate Jammu inaugurates Shiitake Mushroom Cultivation Room A wave of change is sweeping across Gujarat : Bhagwant Mann Senior National Artistic Gymnastics (M/W) Championship- 2022 concluded at LPU campus for team events Our handicrafts are our living heritage; all efforts should be made to promote them : Jagdeep Dhankhar 4 Associates of Lawrance Bishnoi Gang arrested with 3 Pistol, 1 Magazine & 22 live Cartridges Honda Cars India signs agreement with MSTI to offer Music first, trailer later: Promo blueprint for Shah Rukh Khan-starrer 'Pathaan' 'Bigg Boss 16': Tina Datta breaks down on b'day, nomination task leads to rift Yogi Adityanath compares Shivpal Yadav to a pendulum Arjun Kapoor starts shooting for next film in Delhi, says city lucky for him HP&M Dept conducts Awareness Camp at Fruit & Vegetable Market Parimpora, Srinagar JKRLM organises workshop on SHG-Bank Linkage at Shopian DHEW Budgam organizes Awareness programme at Anganwadi Centre Bugroo, Khansahib


Covishield offers protection from 'double mutant', says CCMB

Coronavirus, COVID 19, Novel Coronavirus, India Fights Corona, Fight Against Corona, Corona Virus Updates, Covaxin, Covishield, Covid-19 Vaccine, Covid-19 Vaccine in India, COVID-19 Vaccination, Centre for Cellular and Molecular Biology, CCMB, Indian Council of Medical Research, ICMR

Web Admin

Web Admin

5 Dariya News

Hyderabad , 23 Apr 2021

Covishield vaccine offers protection from double mutant variant of novel coronavirus, shows a study by the Centre for Cellular and Molecular Biology (CCMB).CCMB Director Rakesh K. Mishra termed this as a very preliminary but encouraging result."Early results using in vitro neutralisation assay show that both convalescent (prior infection) sera and Covishield vaccinated sera offer protection against the B.1.617 variant, aka double mutant," he said in a tweet.The CCMB's finding came close on the heels of an announcement by the Indian Council of Medical Research (ICMR) that Covaxin neutralises multiple variants of SARS-CoV-2 and effectively works against the double mutant strain as well.

Covaxin is India's first indigenous Covid vaccine developed by Bharat Biotech in collaboration with ICMR.Covishield has been developed by Oxford-Astrazeneca and is being produced by Serum Institute of India, Pune.Both Covaxin and Covishield are part of India's ongoing Covid vaccination programme.The 'double mutant' (B.1.617) is said to be responsible for the current surge in Covid-19 cases in Maharashtra and other states in India. Scientists earlier feared that vaccines may not offer protection from 'double mutant' as it may escape the immune system.

After the CCMB's latest announcement that Covishield too offers protection from 'double mutant', experts say this again underscore the need for people to get vaccinated.CCMB scientist Divya Tej Sowpati tweeted that the convalescent sera is from September 2020, hence most likely of an infection of a variant which is not B.1.617.He also pointed to misinformation and confusion about the circulating SARS-CoV-2 variants in India.Though B.1.617 is called 'double mutant', it is characterised by more than 15 mutations. "It got dubbed the 'double mutant' because of two spike mutations, L452R and E484Q, which were mutations of concern because of their immune escape properties, and possible high infectivity," wrote Sowpati, who is leading Covid-19 genomics at CCMB.According to him, B.1.618 is not the 'triple mutant'. "Triple Mutant: Again, WRONG name, because it has many more defining mutations. Dubbed 'triple' because in addition to the two mutations, it also has V382L in its Spike. This is a sub-lineage of B.1.617, found mainly in MH samples and also a bit in other states."He also clarified that B.1.618 which was first sampled in West Bengal in late October 2020, has nothing to do with B.1.617, except for a couple of shared variants that all SARS-CoV-2 strains have at this point such as D614G.According to him, the main concern with B.1.618 is that it is found in growing proportions in West Bengal and has the spike del145-146 as well as E484K, both of which are known immune escape mutations.The scientist said that the names of "double" and "triple" mutants are wrong and misleading and that they have no connection to the lineage seen in West Bengal.


Tags: Coronavirus , COVID 19 , Novel Coronavirus , India Fights Corona , Fight Against Corona , Corona Virus Updates , Covaxin , Covishield , Covid-19 Vaccine , Covid-19 Vaccine in India , COVID-19 Vaccination , Centre for Cellular and Molecular Biology , CCMB , Indian Council of Medical Research , ICMR



related news




Photo Gallery



Video Gallery



5 Dariya News RNI Code: PUNMUL/2011/49000
© 2011-2022 | 5 Dariya News | All Rights Reserved
Powered by: CDS PVT LTD