What is Chronic Kidney Disease?
Know how new algorithms revealed by Colombian researchers can identify the risk decades before the onset of kidney disease?
5 Dariya News
20-Jun-2022
Chronic kidney disease, which is also termed asĀ chronic kidney failure, is the process in which the functionality of the kidney reduces gradually to complete failure.
Some symptoms can help you recognize chronic kidney disease:
In the early stages of chronic kidney disease, you may have few signs or symptoms and it is possible that you may not realise that you have kidney disease until the condition is advanced & advanced chronic kidney disease can cause unnecessary and dangerous levels of fluid, electrolytes and waste to build up in your body.
The 2023 #WorldKidneyDay theme is official: Kidney Health for All - Preparing for the unexpected, protecting the vulnerable!
— World Kidney Day (@worldkidneyday) May 30, 2022
Stay tuned for updates on the full campaign launch in September. Until then, join us in celebrating the successful 2022 campaign by sharing your activities pic.twitter.com/QNLWoyFB6w
Chronic kidney disease can progress to the end stage of kidney failure:
Chronic kidney disease can progress to end-stage kidney failure, which is fatal without artificial filtering or kidney transplantation whose treatment usually focuses on controlling the cause and slowing the progression of kidney damage.
The main function of the kidney is to balance the amount of water in the body. The kidney regulates the amount of salt and water in the body. In chronic kidney disease, kidney function gradually decreases. This problem is seen more in women and the elderly. Apart from this, the kidney maintains the chemical balance in the body by filtering the excess water.
Detoxification the prime functionality of the Kidney :
An important function of the kidney is to remove waste, dirt and toxic substances from the body. The role of the kidney is very important in detoxifying the body. The kidney works by throwing out the glucose and protein obtained from the body, which is very important for health.
Gender can be a risk factor for #ChronicKidneyDisease (CKD), as men progress to later stages of the disease sooner. Early diagnosis can help maintain kidney function for longer.
— Kidney Disease Forum (@KidneyDiseaseFm) June 13, 2022
This #MensHealthMonth, encourage at risk men to get tested annually to help detect #CKD early. š¤µ
#ChronicKidneyDisease affects 1 in 10 people globally.
— Kidney Disease Forum (@KidneyDiseaseFm) June 3, 2022
@kidneydiseasfm aims to bring together healthcare professionals, sharing useful resources on the disease, highlighting its link to #Type2Diabetes and #CardiovascularDisease, and encouraging good kidney health.
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Various researches conclude towards the numerous reasons for chronic Kidney disease:
There are many reasons for having chronic kidney disease, the most prominent being diabetes and obesity. Apart from this, high blood pressure, family history related to kidney, stones and excessive use of antibiotics are included. Statistics show that about 195 million women are suffering from this disease worldwide and almost six lakh women are dying due to this disease every year.
Key points to keep in mind for Kidneys better functionality :
Patients with type 2 diabetes and chronic kidney disease who are also on dialysis, are at an increased risk of cardiovascular disease.
— Kidney Disease Forum (@KidneyDiseaseFm) January 26, 2022
Learn what patients can do to try to keep their hearts healthy when on dialysis. #KidneyDisease #ChronicKidneyDisease
New algorithm developed by Colombian researchers to analyse genome types
A new algorithm developed by Columbia University researchers can analyse thousands of genome types and predict a person's risk of developing chronic kidney disease ā and it works in people of African, Asian, European and Hispanic descent.
New trans-ancestry PRS for chronic kidney disease: "The top 2% of the GPS was associated with nearly threefold increased risk of CKD across ancestries." via @NatureMedicine https://t.co/SnXQcEw1Zy
— Jordan Smoller (@jorsmo) June 17, 2022
According to physician-scientist Krzysztof Kiriluk:
Krzysztof Kiriluk, MD, associate professor of medicine and physician-scientist in the department of nephrology at Columbia University's Vagelos College of Physicians and Surgeons, said that with this polygenic method, we are able to identify people at risk decades before the onset of kidney disease. and people at high risk can make protective lifestyle changes to reduce that risk.
New international guidance means more intensive blood pressure-lowering treatment is indicated for more than 10% of patients with chronic kidney disease, who are otherwise at high risk of cardiovascular events. š° Read more on #CRTonline. https://t.co/gDpv1gOVBk pic.twitter.com/XvCblhO47V
— CRT Meeting (@CRT_meeting) May 10, 2022
Research would be useful in reducing the need for transplant or dialysis:
Early detection of kidney disease can prevent many cases of kidney failure and reduce the need for transplant or dialysis.
APOL1 can also control dangerous chronic kidney risk such as:
The study also confirmed that APOL1 is an important risk factor in people of African descent. But even if APOL1 is present in a person, other genes may increase or decrease the risk of developing chronic kidney disease. This information could be important when new drugs are developed specifically for people with APOL1. Krzysztof Kiriluk and his team described their method and tested it on 15 different groups of people, including people of European, African, Asian and Hispanic descent, in a new study published in Nature Medicine, using the algorithm called APOL1. analysed variants of the gene, known to be a common cause of kidney disease in people of African descent, and thousands of other kidney disease variants found in people of all races.